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Open Access Publications from the University of California

Molecular conformations of DNA targets captured by model nanoarrays

  • Author(s): Hao, X
  • Josephs, EA
  • Gu, Q
  • Ye, T
  • et al.

© 2017 The Royal Society of Chemistry. An open question in single molecule nanoarrays is how the chemical and morphological heterogeneities of the solid support affect the properties of biomacromolecules. We generated arrays that allowed individually-resolvable DNA molecules to interact with tailored surface heterogeneities and revealed how molecular conformations are impacted by surface interactions.

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